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Tapinor 1% Cream contains Tapinarof which belongs to a group of medicines called Anti-psoriatics. Tapinor 1% Cream is used to manage plaque psoriasis (a long-lasting autoimmune disease that causes thick scaly patches on the skin) in affected individuals.
Tapinor 1% Cream is not recommended for use in patients allergic to Tapinor 1% Cream. It is also not recommended for use in patients with a history of hypersensitivity reaction (immune response to an allergen), calcium metabolism disorders (due to high/low calcium levels), vitamin D toxicity, and/or severe liver & kidney disease.
Before applying Tapinor 1% Cream, inform your doctor if you are a smoker, undergoing ultraviolet treatment, and/or suffering from exfoliative/pustular psoriasis.
Tapinor 1% Cream is not recommended for use in children (aged below 6 years) and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Tapinor 1% Cream should be used with caution in pregnant women only if it is necessary. Consult your doctor before applying it.
Tapinor 1% Cream should be used with caution in breastfeeding women. It is not recommended to be applied on the breast area while feeding the baby. Consult your doctor before applying the medicine.
Tapinor 1% Cream generally does not have any effect on your ability to drive or use machines. Consult your doctor before applying the medicine.
Tapinor 1% Cream is not recommended for use in patients suffering from severe kidney problems. Consult your doctor before applying the medicine.
Tapinor 1% Cream is not recommended for use in patients suffering from severe liver problems. Consult your doctor before applying the medicine.
Tapinor 1% Cream works by slowing down the excessive production of skin cells.
Tapinor 1% Cream is used to treat a certain skin condition (plaque psoriasis). Tapinarof can help lessen the symptoms of plaque psoriasis (such as red, scaly patches of skin).
This cream contains Tapinarof as the active ingredient. Tapinarof is an Aryl hydrocarbon Receptor (AhR) agonist. The specific mechanisms by which Tapinarof cream exerts its therapeutic action in psoriasis patients are unknown.
Inform your doctor about all the medicines you use, including prescription and non-prescription medicines, and herbal supplements.
Hypersensitive to any of its components.
Pregnancy: The available data on Tapinarof cream use in pregnant women are insufficient to evaluate for a drug-associated risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes. In animal reproduction studies, subcutaneous administration of Tapinarof to pregnant rats and rabbits during the period of organogenesis resulted in no significant adverse effects at doses 268 and 16 times, respectively, the maximum recommended human dose (MRHD). The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. All pregnancies have a background risk of major birth defects, loss, and other adverse outcomes.
Lactation: No data are available regarding the presence of Tapinarof in human milk or the effects of Tapinarof on the breastfed infant or on milk production. Tapinarof was detected in rat offspring following subcutaneous administration to pregnant female rats which suggests that tapinarof was transferred into the milk of lactating rats. When a drug is present in animal milk, it is likely that the drug will be present in human milk. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for Tapinarof cream and any potential adverse effects on the breastfed infant from Tapinarof cream or from the underlying maternal condition.
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